Q: Beside diuresis describe 2 more effects of furosemide (Lasix)?
Answer: Lasix is a diuretic which acts on the loop of henle and inhibits reabsorption of both sodium and chloride ions. Beside this basic function of diuresis
1. Lasix also causes peripheral vasodilation (mostly venodilatation) and an increase in systemic venous capacitance. Obviously this helps with the CHF patients.
2. Lasix reduces ICP and can be use in conjunction with Mannitol. By interfering with the Na transport which in turn slows the production of CSF fluid from the choroid plexi.