Saturday, July 2, 2011


Q: Out of all Quinolones which is reported worse to cause CNS symptoms?

Answer: Moxifloxacin


Moxifloxacin is reported as worst among all quinolones for causing CNS toxicity which includes tremor, confusion, anxiety, insomnia, agitation, psychosis or even seizure.


Galatti L, Giustini SE, Sessa A, et al. - "Neuropsychiatric reactions to drugs: an analysis of spontaneous reports from general practitioners in Italy" , Pharmacological Research, Volume 51, Issue 3, March 2005, Pages 211-216